
Infections represent a significant cause of morbidity and mortality among immunocompromised individuals, particularly cancer patients undergoing immunosuppressive therapies such as chemotherapy, radiotherapy, or stem cell transplantation.
The compromised immune response in these patients reduces their ability to mount effective defenses against common and opportunistic pathogens. Neutropenia, mucosal barrier injury, and immune dysregulation are among the key risk factors that predispose cancer patients to severe infections.
Moreover, the emergence of multidrug-resistant organisms and the frequent need for invasive procedures further complicate infection management. Early detection, prophylactic strategies, and prompt initiation of targeted antimicrobial therapy are critical to improving clinical outcomes.
In this panel, we will present a case of hematologic malignancy complicated by an infection with multidrug-resistant microorganisms. The objective of this case presentation is to highlight the challenges posed by multidrug-resistant Gram-negative and Gram-positive bacteria, with a focus on therapeutic management and strategies to prevent their transmission.